Tuesday, May 7, 2019
5:00 pm - 7:30 pm
Registration
6:00 pm - 7:30 pm
Cocktail Reception
Sponsored by: Our Diamond Sponsor, Aptar Pharma and Our Gold Sponsors, 3M Drug Delivery Systems, Catalent, Hovione
Wednesday, May 8, 2019
7:30 am
Registration & Welcome Coffee
8:30 am
Welcome Address & Introduction
Richard N. Dalby, Ph.D., Professor, School of Pharmacy, University of Maryland, Baltimore, Maryland USA
8:45 am
PLENARY LECTURE
Sponsors: Our Diamond and Gold Sponsors Moderator: Richard N. Dalby, Ph.D.
Unraveling Triple Therapy in Chronic Obstructive Pulmonary Disease Jadwiga A Wedzicha, F.Med.Sci., Imperial College London, London, United Kingdom
9:30 am
Refreshments, Scientific Poster Session & Technology Exhibition
Light Refreshments Served
Sponsors: Our Gold Sponsors Moderator: Richard N. Dalby, Ph.D.
Scientific Posters & Exhibit Tables will be available for viewing between 9.30 a.m. and 6.00 p.m.
10:00 am - 12:00 pm
SESSION 1: New Approaches to Treating Respiratory Diseases
Sponsor: AstraZeneca Moderator: M. Geraldine Venthoye, Ph.D.
10:00 am
Can Emphysema Be Reversed? Preclinical Evidence Via Local STAT3/VEGF Stimulation Masahiro Sakagami, Ph.D., Virginia Commonwealth University, Richmond, Virginia
10:30 am
Cross-Talk between Gut and Lung Microbiomes: Implications for Chronic Respiratory Disease Philip Hansbro, Ph.D., Centenary Institute and University of Technology, Sydney, Ultimo, NSW, Australia
11:00 am
Improving Inhaled Antibiotic Treatment Against Respiratory Biofilm Infections Hui Xin Ong, Ph.D., Woolcock Institute of Medical Research, Glebe, NSW, Australia
11:30 am
Cystic Fibrosis Gene Therapy: Improving Lung Gene Transfer Using Lentiviral Vectors Eric W.F.W Alton, M.D., Imperial College London, London, United Kingdom
12:00 pm
Scientific Poster Session & Technology Exhibition
Lunch Provided
2:00 pm - 6:00 pm
SESSION 2: Workshops
Sponsor: Aptar Pharma Moderator: Gerallt Williams, Ph.D.
2:00 pm
Workshop Selection #1
3:15 pm
Workshop Selection #2
4:30 pm
Workshop Selection #3
The following companies each sponsored 60-minute interactive presentations on new technologies and services related to nasal and pulmonary drug delivery. Meeting participants could select and attend three of these sessions.
Refreshments will be available throughout the afternoon.
Aptar Pharma & Propeller Health (Room C7) The Future of Connected Medicines: Promise and Potential Pitfalls
Biocorp (Room C3) Using Connected Compliance Monitoring Solutions in the Context of Clinical Trials for New Respiratory Medicines
Emergo (Room D1) Inhaler Use in Real Life: Using Human Factors to Understand Risk and Critical Design Attributes
FLUIDDA (Room C5) FRI Deposition: Next Generation Aerosol Deposition and Delivery Optimization
H&T Presspart (Room D2) The Future Challenges Facing Respiratory Drug Delivery: Stability and Effective Delivery of Complex Molecules and Combinations Meeting Patient Needs
Harro Höfliger (Room D3) Challenges in the Development Process for Soft Mist Inhaler Design, Manufacturing and Scale-Up
Hovione (Room F7) Bridging Particle Engineering, Formulation and Device Development
IMA (Room C2) Manufacturing DPIs: An Engineering Perspective
Lonza (Room F1) Technology Selection for Capsule-Based Inhalation Product Development
Mexichem (Room F3) HFA 152a - The Next Chapter in the Story of the MDI?
Proveris Scientific (Room F5) Control Strategy for pMDI Development and Release Testing: Factors that Impact pMDI Performance
Qualicaps (Room F6) The Performance of Hard Shell Capsules for Use in Dry Powder Inhalers
Thursday, May 9, 2019
Sponsors: Our Gold Sponsors Moderator: Richard N. Dalby, Ph.D. Scientific Posters & Exhibit Tables will be available for viewing between 8.30 a.m. and 6.00 p.m.
8:30 am - 10:00 am
SESSION 3: Pipes, Particles and Predictions: New Insights into Deposition
Sponsors: Our Gold Sponsors Moderator: Darragh Murnane, Ph.D.
Combining Computational Fluid Dynamics and Discrete Element Method Modeling with Experiments to Predict Dry Powder Inhaler Performance Kyrre Thalberg, Ph.D., AstraZeneca, Gothenburg, Gothenburg, Sweden
9:00 am
Prediction of Intersubject Variability of Extrathoracic Deposition in Adults and Children Warren H. Finlay, Ph.D., University of Alberta, Edmonton, AB, Canada
Is Aerodynamic Diameter a Good Metric for Understanding Regional Lung Deposition? Jeffry Weers, Ph.D., Respira Therapeutics, Burlingame, California
10:30 am - 12:00 pm
SESSION 4: Posters on the Podium
Sponsor: Vectura Moderators: Joanne Peart, Ph.D., and Daniela Traini, Ph.D. Five poster authors have been selected to summarize their work and answer questions during a fast-paced interactive podium session.
Aerosol Evolution and Deposition in the Human Upper Respiratory Tract Mahdi Asgari, Ph.D., Philip Morris International, Neuchatel, Switzerland
10:45 am
Numerical Modeling of Binary Collision of Adhesive Units Sohan Sarangi, M.S., Uppsala University, Uppsala, Sweden
Spray Drying of Inhalable Biopharmaceuticals of Increasing Size and 3D Structure Complexity: From 30 to 250 kDa Diana A. Fernandes, M.Sc., Hovione, Loures, Portugal
11:15 am
Agitation Method Affects Colloidal Stability of Pharmaceutical Suspensions Hui Wang, Ph.D., University of Alberta, Edmonton, Alberta, Canada
Use of Biophysical Modeling to Develop Indacaterol/Glycopyrronium/Mometasone Furoate Inhaled Combination: Results from a Salt-Bridging Study of Indacaterol in Patients with Asthma Juergen Jauernig, Ph.D., Novartis, Basel, Switzerland
11:45 am
Presentation of VCU RDD Peter R. Byron Graduate Student Award
Lunch provided
2:00 pm - 5:45 pm
SESSION 5: Re-inventing Inhalers for the Digital Age
Sponsor: H&T Presspart Chairperson: Igor Gonda, Ph.D., Respidex, San Francisco, California, USA
myAirCoach: Asthma Management Using mHealth, Sensors, and Environmental Parameters Persijn Honkoop, Ph.D., Leiden University Medical Center, Leiden, Netherlands
2:30 pm
Improving Inhaler Technique Using Real-time Identification of Device Errors with Smart Inhalers Henry Chrystyn, Ph.D., Inhalation Consultancy, Leeds, Yorkshire, United Kingdom
3:00 pm
The Sound of Adherence: Validating Acoustic Methods to Assess Inhaler Technique Terence E Taylor, Ph.D., Trinity College Dublin, Dublin, Ireland
3:30 pm
4:00 pm
Designing Connected Devices for Inhalation: Lessons Learned from Injectables Kevin Deane, B.Sc., Phillips-Medisize, Milton, Cambridge, United Kingdom
Intellectually Smart Devices: Navigating Patent Risks in the Age of Intelligent Inhalers Gwilym J.O. Attwell, J.D., Fish & Richardson, Wilmington, Delaware
5:00 pm
Panel Discussion
Chairperson and Advocate: Igor Gonda, Ph.D., Respidex, San Francisco, California, USA Panel: Gwilym Attwell, Fish & Richardson Henry Chrystyn, Inhalation Consultancy Kevin Deane, Phillips-Medisize Persijn Honkoop, Leiden University Medical Center Terence Taylor, Trinity College Dublin
Chairperson and Advocate: Igor Gonda, Ph.D., Respidex, San Francisco, California, USA
Panel: Gwilym Attwell, Fish & Richardson Henry Chrystyn, Inhalation Consultancy Kevin Deane, Phillips-Medisize Persijn Honkoop, Leiden University Medical Center Terence Taylor, Trinity College Dublin
7:30 pm
Gala Dinner
Sponsored by Please assemble in front of the Estoril Congress Center at 6.30 p.m. Buses will depart from the Congress Center at 6.45 p.m., for the approximately 30-minute drive to Sud Lisboa. Return by bus between 10.30 p.m. and 1.00 a.m.
Friday, May 10, 2019
Sponsors: Our Gold Sponsors Moderator: Richard N. Dalby, Ph.D. Scientific Posters & Exhibit Tables will be available for viewing between 8.30 a.m. and 12.30 p.m.
8:30 am - 9:30 am
SESSION 6: Take a Deep Breath: Brexit and Environmental Sustainability
Sponsor: Chiesi Farmaceutici Moderator: Vidya Swaminathan, Ph.D.
Regulatory Alignment Between the United Kingdom and Europe Post Brexit David Jefferys, M.D., Eisai Europe, Hatfield, Hertfordshire, United Kingdom
Sustainable Respiratory Healthcare: Environmental Impact of Inhalers Alexander J. Wilkinson, B.M., B.Ch., East and North Hertfordshire NHS Trust, Stevenage and Centre for Sustainable Healthcare, Oxford, United Kingdom
10:00 am - 11:45 am
SESSION 7: New Approaches to Inhalation Product Development and Production
Sponsor: MEGGLE Moderators: Richard N. Dalby, Ph.D., and Changning Guo, Ph.D.
Supporting Inhalation Drug-Device Combination Product Quality Using 3D Printing Technology Xiaofei Liu, Ph.D., U.S. Food & Drug Administration, St. Louis, Missouri
Multiscale Tomography: Probing the Nano-, Micro-, and Meso-scale Resolution of Inhalation Powder Structure Parmesh Gajjar, Ph.D., University of Manchester, Manchester, United Kingdom Ioanna Danai Styliari, Ph.D., University of Hertfordshire, Hatfield, United Kingdom
Continuous Processing: Challenging the Current Manufacturing Paradigm for Dry Powder Inhalers Eunice Costa, Ph.D., Hovione, Lisboa, Portugal
Buffet Lunch provided
End of RDD Europe 2019
